So far, I have gotten to the point of creating the
spheroids of the pancreatic cancer cells. Creating the spheroids is in and of
itself the beginning of the process, but a process of its own. After the
spheroids are created, we will test certain drugs on the cells. The specific
drugs are to be decided, although the one certain drug is Triptolide, which is
believed to inhibit cell growth. That is the direction of the project in the
future, but for now, the focus is on growing the spheroids. These spheroids must
be grown carefully using the sterile technique in order to prevent
contamination, but once this arduous process is completed, we will move on to
the drug testing.
Monday, February 27, 2017
Tuesday, February 14, 2017
Abstract/Project Beginning
Scientists can use 3-D models of pancreatic cancer cells to
understand the ways in which they work and interact with surroundings. This
experiment starts off with the development of spheroids, which are the
above-mentioned models. After these spheroids are developed, the project can go
in many different directions. The current plan is to experiment on the
metabolic pathways. Pancreatic cancer cells tend to do glycolysis. So, the
experiment will definitely attempt to check how their glycolysis can be
altered. However, there is also potential for drug testing. Certain drugs can
be tested, and how these drugs affect the cells can be measured.
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